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Area of Research

• Identification, biochemical characterization and modification of Carbohydrate Active Enzymes (CAZymes), especially from (hyper)thermophilic microorganisms, for their exploitation in lignocellulosic biomasses and waste products hydrolysis and valorisation
• Isolation, identification, purification and biochemical characterization of protein molecules from different natural sources, including cold-adapted proteins from polar organisms.
• Innovative biocatalysts involved the carbon cycle for CO₂ sequestration processes and the production of valuable four-carbon compounds
• Functional characterization of nutrient-sensing mechanisms in marine diatoms for biomass production
• Use of the recombinant DNA technology for the heterologous overexpression of enzymes as well as their immobilisation to the Escherichia coli outer membrane
• Enzymes  involved in DNA replication, maintenance  and repair: analysis, characterization  and their possible biotechnological applications, pointing the gaze to biosensors

Area of Expertise and Main Technologies

• Biochemistry, Enzymology, Molecular Biology, Microbiology and Biotechnology
• Discovery and biochemical/biophysical characterization of proteins and enzymes from different sources, including extremophilic organisms
• Protein expression and purification; protein engineering
• Protein-protein interaction analysis by Surface Plasmon Resonance (SPR) and BioLayer Interferometry (BLI) techniques
• Chemo-enzymatic reaction for biosensor-derived immobilization and innovative product syntheses

Key Organisms

• Archaea 
• Bacteria
• Diatoms

Industrial Application

• Valorisation of different waste products, including lignocellulosic biomasses, for the synthesis of new molecules with high added value 
• Use of innovative thermostable protein tags for enzymatic immobilization in biosensors and synthesis of products with high added value

Industrial Sector

• Bulk & Fine Chemicals 
• Energy
• Food Ingredients
• Material & Textiles
• Pharma

Contacts 

Main contact: Beatrice Cobucci-Ponzano - beatrice.cobucciponzano@ibbr.cnr.it

Clemente Capasso - clemente.capasso@ibbr.cnr.it

Vincenzo Carginale - vincenzo.carginale@ibbr.cnr.it

Maria Antonietta Ciardiello - mariaantonietta.ciardiello@ibbr.cnr.it

Stefania Crispi - stefania.crispi@ibbr.cnr.it 

Mariarosaria De Falco - mariarosaria.defalco@ibbr.cnr.it

Mariarita De Felice - mariarita.defelice@ibbr.cnr.it

Stefania Filosa - stefania.filosa@ibbr.cnr.it 

Daniela Giordano - daniela.giordano@ibbr.cnr.it

Giuseppe Perugino - giuseppe.perugino@ibbr.cnr.it

Alessandra Rogato - alessandra.rogato@ibbr.cnr.it

Maurizio Tamburrini - maurizio.tamburrini@ibbr.cnr.it