Consiglio Nazionale delle Ricerche
Istituto di Bioscienze e BioRisorse
Identification and characterization of proteins and enzymes (Cazymes), especially those from organisms growing in extreme environments for applications in Green Chemistry, Synthetic Biology, and Sustainable Bioenergy.
Area of Research
- Identification, biochemical characterization and modification of Carbohydrate Active Enzymes (CAZymes), especially from (hyper)thermophilic microorganisms, for their exploitation in lignocellulosic biomasses and waste products hydrolysis and valorisation
- Isolation, identification, purification and biochemical characterization of protein molecules from different natural sources, including cold-adapted proteins from polar organisms.
- Innovative biocatalysts involved the carbon cycle for CO2 sequestration processes and the production of valuable four-carbon compounds
- Functional characterization of nutrient-sensing mechanisms in marine diatoms for biomass production
- Use of the recombinant DNA technology for the heterologous overexpression of enzymes
- Enzymes involved in DNA replication, maintenance and repair: analysis, characterization and their possible biotechnological applications, pointing the gaze to biosensors
- Characterization of bioactive molecules from natural sources in mammialian cells
Expertise and Main Technologies
- Biochemistry, Enzymology, Molecular Biology, Microbiology and Biotechnology
- Discovery and biochemical/biophysical characterization of proteins and enzymes from different sources, including extremophilic organisms
- Protein expression and purification; protein engineering
- Protein-protein interaction analysis by Surface Plasmon Resonance (SPR) and BioLayer Interferometry (BLI) techniques
- Chemo-enzymatic reaction for biosensor-derived immobilization and innovative product syntheses
Key Organisms
Archea
Bacteria
Diatoms
Industrial Applications
- Valorisation of different waste products, including lignocellulosic biomasses, for the synthesis of new molecules with high-added value
- Use of innovative thermostable protein tags for enzymatic immobilization in biosensors and synthesis of products with high-added value
Industrial Sector
Bulk & Fine Chemicals
Energy
Food Ingredients
Material & Textiles
Pharma
Scientific References
Angela
Capaccio
Researcher
Clemente
Capasso
Researcher
Vincenzo
Carginale
researcher
Stefania
Crispi
RESEARCHER
Beatrice
Cobucci Ponzano
national node Coordinator
Nicola
Curci
RESEARCHER
Mariarosaria
De Falco
RESEARCHER
Mariarita
De Felice
RESEARCHER
Federica
De Lise
RESEARCHER
Mauro
Di Fenza
infrastructure manager
Stefania
Filosa
RESEARCHER
Daniela
Giordano
RESEARCHER
Alessandra
Rogato
RESEARCHER
Cinzia
Verde
RESEARCHER
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