UNIVERSITAS STUDIORUM INSUBRIAE​

Università degli Studi dell'Insubria

Production and characterization of recombinant proteins for different fields of biotechnology. In silico design and protein engineering for novel enzymatic activities.

The team founded the “The Protein Factory” (www.theproteinfactory.it), promoting basic and applied research on proteins of biotechnological relevance.

Area of Research

  • Protein production and engineering
  • Valorization of lignin and chitin
  • D-amino acids production
  • Plastic degradation
  • Strain improvement for antibiotics and amino acid enantiomers

Expertise and Main Technologies

    • Enzyme discovery, engineering and characterization
    • Enzymatic and microbial bioconversion
    • Morphological analysis of enzymatic activity
    • System biocatalysis: set-up of novel metabolic pathways
    • Rational genetic engineering for increasing the production of specialized metabolites
    • Development of fermentation processes
    • Targeted metabolic analysis

Key Organisms

E. coli

Actinomycetes

Yeasts

Fish

Industrial Applications

    • Production of pure amino acid enantiomers
    • Production of cis,cis-muconic acid
    • Production of glycopeptide antibiotics
    • PET enzymatic degradation

Industrial Sector

Pharma

 

Energy

 

Bulk & Fine Chemicals

 

Biological & Biomedical

Scientific References

Loredano
Pollegioni

Full professor

Immacolata
Serra

principal investigator

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