Università degli studi dell'Insubria - Uninsubria

Università degli studi dell'Insubria - Uninsubria

Production and characterization of recombinant proteins for different fields of biotechnology. In silico design and protein engineering for novel enzymatic activities

The team founded the “The Protein Factory” (www.theproteinfactory.it), promoting basic and applied research on proteins of biotechnological relevance.

Area of Research

  • Protein production and engineering
  • Valorization of lignin and chitin
  • D-amino acids production
  • Plastic degradation
  • Strain improvement for antibiotics and amino acid enantiomers

Area of Expertise and Main Technologies

  • Enzyme discovery, engineering and characterization
  • Enzymatic and microbial bioconversion
  • Morphological analysis of enzymatic activity
  • System biocatalysis: set-up of novel metabolic pathways
  • Rational genetic engineering for increasing the production of specialized metabolites
  • Development of fermentation processes
  • Targeted metabolic analysis

Key Organisms

  • E. coli
  • Actinomycetes
  • Yeasts
  • Fishes

Industrial Application

  • Production of pure amino acid enantiomers
  • Production of cis,cis-muconic acid
  • Production of glycopeptide antibiotics
  • PET enzymatic degradation

Industrial Sector

  • Pharma
  • Energy
  • Bulk & Fine Chemicals
  • Biomedical & Biological


Loredano Pollegioni - loredano.pollegioni@uninsubria.it

Elena Rosini - elena.rosini@uninsubria.it


Modification date : 25 April 2023 | Publication date : 17 April 2022 | Redactor : Mauro Di Fenza