Università degli Studi di Milano Bicocca - UNIMIB

Università degli Studi di Milano Bicocca - UNIMIB

Genetic improvement of microbial strains of industrial interest, metabolic engineering, control and validation of fermentation processes in use in the pharmaceutical, chemical, food and environmental industry.

The team founded the “Bicocca Biotechnicum Center” a facility were pre-pilot bioprocess can be studied and developed.

Area of Research

Our group is interested in the development of sustainable microbial-based bioprocesses, mainly valorizing residual biomasses as in the concept of biorefineries. This is pursued by tailoring microbial strains for the production of fine and bulk chemicals, biofuels, nutraceuticals, innovative materials and additives. Synthetic biology, metabolic engineering, screening protocols and adaptive laboratory evolution are the approaches used to leverage microbial potential, including robustness against stress, to match industrial requirements.  

Area of Expertise and Main Technologies

Industrial Microbiology, Fermentations and Bioreactors, Metabolic Engineering, Synthetic Biology, Quantitative Microbial Physiology, Biocatalysis.

Key Organisms

Yeasts (Saccharomyces cerevisiae and non-Saccharomyces yeasts). 

Industrial Application

Our research matches industrial requirements for a change from linear to circular processes of production, as microorganisms and enzymes can valorize and up-cycle residual (bio)masses into novel products or products that can substitute those produced from fossil resourses and with high environmental impacts. We start from proof of concept and develop the potential process of production up to 10L scale bioreactor.  

Industrial Sector

  • Material & Textiles
  • Bulk & Fine Chemicals
  • Food Ingredients


Paola Branduardi - paola.branduardi@unimib.it

Immacolata Serra - immacolata.serra@unimib.it


Modification date : 14 March 2024 | Publication date : 17 April 2022 | Redactor : Mauro Di Fenza